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  CYCLODEXTRIN PLATFORM
Cycloxome™
  TAILORED DEVELOPMENT
Cycloxome™

The Smallest Delivery Systems

CycloXome™ are actives entrapped inside cyclodextrins. The active is strongly bound inside the cavity of the cylinder-shaped cyclodextrin, protected from oxidation and depletion.

Because its outer surface is positively charged, cyclodextrin fixates strongly on the skin surface, negatively charged. But also because it is charged, cyclodextrin cannot cross the skin barrier.

3D representation of active included in CycloXome™
 
Benefits in Cosmetics
No penetration
Slow and prolonged release of the active
Reduce undesired cytotoxicity
Reduce irritation potential
Mask odour
Water soluble
Colorless and transparent

Cyclodextrin is not only perfectly safe but it also increases the safety of the encapsulated actives without affecting their efficiency: because the release is slow and progressive, CycloXome™ avoids reaching toxic concentrations of the encapsulated actives. The ability of CycloXome™ to reduce irritancy was demonstrated in a patch test with glycolic acid.
 

Powered by CycloXome™: CycloPEEL™ , CycloCOOL™ (Menthol), Tea Tree Oil

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