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CycloXome™
The smallest delivery systems

CycloXome™ is active molecule entrapped inside cyclodextrin. The active is strongly bound inside the cavity of the cylinder-shaped cyclodextrin, protected from oxidation and depletion.

Because its outer surface is positively charged, cyclodextrin fixates strongly on the skin surface, negatively charged. But also because it is positively charged, cyclodextrin cannot cross the skin barrier. Therefore, CycloXome™ fixes on the skin but doesn’t penetrate it.

While on the skin, CycloXome™ releases slowly the active, maintaining a balance between the concentration of the intact CycloXome™ , the free active and the empty CycloXome™.

This mechanism has two major consequences:
The availability of the active ingredient is prolonged in time, thus increasing the total bioavailability
The free form is present at all times at low concentration, thus reducing active’s toxicity, irritation, undesired smell, etc.

Benefits
No penetration
Slow and prolonged release of the active.
Reduce undesired cytotoxicity
Reduce irritation potential
Mask odor
Colorless and transparent



Powered by CycloXome™: Glycolic Acid, Salicylic Acid, Arbutin, Azelaic Acid, Hydroquinone, Menthol, Tea Tree Oil


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